Period: 2nd
ECTS: 4
Course contents:
1st Block.
- Biostatistics
- Data Mining and Functional Genomics.
- Sequence Analysis.
2nd Block
- Introduction to Protein Structure. Protein Folding.
- Molecular Dynamics.
- Normal Mode Analysis
- Homology modelling of protein structures
- Some notions of molecular docking for drug design
3rd Block.
- Molecular Evolution.
- Evolution Rates and Phylogenetics.
- Evolution of protein folding stability and protein structures: Classification and Modelling.
Bibliography: Suggested books:
– Graur, D., Li, W.H. (2000) Fundamentals of molecular evolution,
Sinauer, Sunderland. *
– W.J. Ewens, G.R. Grant (2001) Statistical methods in Bioinformatics: An introduction. Springer Verlag, New York **
– NH Barton, DEG Briggs, JA Eisen, DB Goldstein and NH Patel (2007) Evolution Cold Spring Harbor Laboratory Press *
Faculty:
Coordindor. Ugo Bastolla
Email: ubastolla@cbm.csic.uam
Website: http://ub.cbm.uam.es
More info on the course official guide (Guía docente)